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根據美國華盛頓州的西雅圖市福瑞德哈金森腫瘤研究中心(Fred Hutchinson Cancer Research Center)一項新的研究結果,魚油膠囊主成份 ω-3 脂肪酸,竟然可能與前列腺癌(攝護腺腫瘤)有關。
2011 年時,福瑞德哈金森腫瘤研究中心研究顯示血中 DHA 濃度較高,可能加倍得到前列腺癌的機率,稍後歐洲有一較大規模的實驗,也得到同樣結果,這次研究的研究,更進一步探討三種 ω-3 脂肪酸,包括 DHA(docosahexaenoic acid;22:6 ω-3)、EPA(eicosapentaenoic acid;20:5 ω-3) 與DPA(all-cis-7,10,13,16,19-docosapentaenoic acid;clupanodonic acid;22:5 ω-3)。
這項研究統計 834 位得到前列腺癌的病人,其中有 156 位是高分期,也就是說較嚴重的前列腺癌病人,另外,再從 35,500 位未得到前列腺癌的病人之中隨機選出 1,393 人,雙方資料互相比較。
ω-3 脂肪酸與前列腺癌的數據研究
研究發現,吃最多 ω-3 脂肪酸的人,平均血液中的ω-3脂肪酸濃度比吃最少的人高出 2.5%──這表示吃 ω-3 脂肪酸的確「有效」提升了血液中的 ω-3 脂肪酸濃度。
然而,血中高 ω-3 脂肪酸濃度的人,得到高期別前列腺癌的機率,高出 71%,得到低期別前列腺癌的機率,也高出 44%,總體來說,得到前列腺癌的機率比一般人多出 43%。
以往認為魚油中的 ω-3 脂肪酸對身體有益,或是頂多只是增加熱量,然而,福瑞德哈金森腫瘤研究中心重覆了 2011 年的研究結果,顯示 ω-3 脂肪酸非常可能與前列腺癌有關,其中,與高期別的前列腺癌關係較大,更值得關注。
高期別的前列腺癌致死率高
前列腺癌是一種成長速度很慢的腫瘤,又好發於男性年長者,若是低期別的前列腺癌,往往終其一生,癌症都還沒造成任何影響,患者就已經先因為別的疾病過世,也就是說雖然也叫癌,但是一點都不可怕。
不過,高期別的前列腺癌就不同,若病變超出前列腺包膜,不治療的話,10 年內將有一半會發生轉移,最後有 75% 機率會死於前列腺癌;而若診斷時就已經發生遠處轉移的患者,往往診斷後 3 年內就因此而死。也就是說是真正的殺手。
偏偏研究顯示,ω-3 脂肪酸與高期別的前列腺癌關聯更大,過去對魚油膠囊的看法可能需要重新評估了。
這項研究的資料來源,是整理自先前硒與維他命 E 抗癌與否的研究資料,該研究的結果是硒與維他命 E 對抗癌沒有幫助,但是維它命 E 吃多了,也一樣反而會增加前列腺癌的風險,看來想要靠吃藥丸保健康,恐怕不但無效,還可能反而傷身啊。
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